Essential Functions: This position will be involved in a NIH-funded project to study the roles of microRNAs in corneal resident macrophages and in bacterial keratitis through its regulation on innate and adaptive immunity using transgenic mouse models and human corneal samples. The project also will explore the potential of miRNAs as therapeutic targets and develop miRNA-based therapy for bacterial keratitis and related immune/inflammatory diseases. The research will be conducted with comprehensive genetic, cellular and molecular biology and immunological techniques, including flow cytometry, cell sorting, cell culture, gene expression profiling by real time PCR, RNA seq, single cell seq, and immunohistochemistry.
Qualifications: Qualified candidates must have a MD and/or PhD degree(s) in ocular sciences, immunology, molecular biology, molecular genetics and cell biology.Highly self-motivated candidates with passion to such research are encouraged to apply.
Internal Number: 76_206074
About Wayne State University
Founded in 1868, Wayne State University is a nationally recognized metropolitan research institution offering more than 400 academic programs through 13 schools and colleges to nearly 32,000 students. Wayne State?s main campus in Midtown Detroit comprises 100 buildings over nearly 200 acres; its five extension centers offer higher education to people throughout Southeast Michigan. Wayne State is dedicated to preparing students to excel by combining the academic excellence of a major research university with the practical experience of an institution that by its history, location and diversity represents a microcosm of the world we live in. Reflecting its location and the excellent international reputation of its graduate schools, particularly in the sciences, Wayne State boasts the most diverse student body among Michigan?s public universities. Its students represent 49 U.S. states and more than 60 countries.