Essential Functions: Understanding pathways that chemosensitize lung, breast and ovarian cancer cells to cisplatin treatment and the elucidating the mechanism of APOBEC3 induced activation of Base Excision Repair and Mismatch Repair in mediating cisplatin censitivity. Interest and area of knowledge in Lung Cancer, Ovarian Cancer, Breast Cancer, DNA repair, mammalian tissue culture, cell transfection, protein detection via western blots, protein purification, and preparation of cell lysates, apoptosis assays and western blot etc.Oversee all lab functions, including research supplies, tracking inventory, train technical staff, and oversee graduate students working in the lab, grant writing for internal and external funding and manuscript writing.
Qualifications: PhD required, with 4 or more years hands on experience in a research lab.Cell Biology techniques including tissue culture, and transfection, apoptosis, RNA/DNA extraction, Electrophoresis Assay, Plaque Assay, Western Blot, Microarray Analysis, DNA repair assays and ability to perform all functions and duties listed above.
Internal Number: 76_206382
About Wayne State University
Founded in 1868, Wayne State University is a nationally recognized metropolitan research institution offering more than 400 academic programs through 13 schools and colleges to nearly 32,000 students. Wayne State?s main campus in Midtown Detroit comprises 100 buildings over nearly 200 acres; its five extension centers offer higher education to people throughout Southeast Michigan. Wayne State is dedicated to preparing students to excel by combining the academic excellence of a major research university with the practical experience of an institution that by its history, location and diversity represents a microcosm of the world we live in. Reflecting its location and the excellent international reputation of its graduate schools, particularly in the sciences, Wayne State boasts the most diverse student body among Michigan?s public universities. Its students represent 49 U.S. states and more than 60 countries.